Neonatal Fulminant Hepatitis B: Structural and Functional Analysis of Complete Hepatitis B Virus Genomes from Mother and Infant
نویسندگان
چکیده
منابع مشابه
Multiplication of hepatitis B virus in fulminant hepatitis B.
The presence in serum of hepatitis B e antigen (HBeAg) and hepatitis B virus DNA, which are each regarded as reflecting multiplication of hepatitis B virus, were looked for one to five days after the onset of hepatic encephalopathy in 64 patients with fulminant hepatitis B. HBeAg and hepatitis B virus DNA were found in the serum of only 24 (37%) and six (9%) patients, respectively. Hepatitis B ...
متن کاملComplete nucleotide sequence of hepatitis B virus isolated from two infants with fulminant hepatitis.
Kenji Abe*, Tetsuya Kiuchi, Naoto Aiba, Huy Thien-Tuan Tran, Xin Ding, Mari Yamaguchi, Tetsutaro Sata and Koichi Tanaka Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Department of Transplantation and Immunology, Kyoto University Faculty of Medicine, Kyoto 606-8501, Department of Developmental Medical Sciences, Graduate School of Medicine, University of Toky...
متن کاملComplete hepatitis B virus genome analysis in HBsAg positive mothers and their infants with fulminant hepatitis B
BACKGROUND After perinatal transmission of hepatitis B virus, infants of anti-HBe positive HBsAg carrier mothers may develop fulminant hepatitis B. Previously it has been suggested, that fulminant hepatitis B in adults was associated with specific mutations in the HBV-genome. The aim of this study was to investigate, whether specific viral variants are associated with fulminant hepatitis B in y...
متن کاملMutations at Nucleotide 1762, 1764 and 1766 of Hepatitis B Virus X Gene in Patients with Chronic Hepatitis B and Hepatitis B-Related Cirrhosis
Abstract Background and objective: Hepatitis B virus (HBV) is a DNA virus with high tendency toward hepatic tissue. There are currently about 3 million HBV-infected people and 350 to 400 million chronic carriers of this virus in the world. X protein plays a role in the over-expression of oncogenes, carcinogenicity of liver cells and overlaps with the basal co...
متن کاملAnti-Hepatitis B Virus Activity of Flavonoids from Marchantia convoluta
Flavonoids from Marchantia convoluta (MCF) were studied for their ability to inhibit the proliferation of 2.2.15 cells. All concentration of MCF inhibited the secretion of HBsAg and HBeAg in the cultured medium by 2.2.15 cells. Analysis of morphological changes of MCF-treated cells by phase-contrast microscopy revealed a possible mode of action for MCF: inhibition of proliferation of 2.2.15 cel...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 1998
ISSN: 0022-1899,1537-6613
DOI: 10.1086/515269